Biosafety Cabinet Manufacturer

Biosafety cabinets (BSCs) are classified into three main types based on protection level and airflow design:

• Class I – Provides personnel and environmental protection but does not protect the product.
• Class II (A2 & B2) – Ensures personnel, product, and environmental protection; commonly used in clinical, pharma, and biotech labs.
• Class III – Offers maximum containment for handling highly infectious or hazardous pathogens (BSL-3 & BSL-4 labs).

To choose the right biosafety cabinet, consider:
Biosafety Level (BSL): Class I (BSL-1/BSL-2), Class II (BSL-2/BSL-3), Class III (BSL-3/BSL-4)
Type of Work: Microbiological research, pharmaceutical testing, cell culture, pathogen handling
Chemical Use: If using toxic chemicals, opt for Class II Type B2 or Class III BSC
Regulatory Compliance: Ensure the cabinet meets NSF/ANSI 49, EN 12469, and WHO guidelines

The price of biosafety cabinets varies based on size, class type, filtration system, and certifications:

• Class I BSC: ₹1.5 – ₹3 Lakhs ($2,000 – $4,000)
• Class II A2/B2 BSC: ₹3 – ₹8 Lakhs ($4,000 – $10,000)
• Class III BSC: ₹10 – ₹20 Lakhs ($12,000 – $25,000)

Note: Prices vary based on customizations, compliance certifications, and additional features.

Regular maintenance ensures optimal performance and safety compliance:
HEPA Filter Replacement: Every 12–18 months (depending on usage)
Airflow Validation & Testing: Every 6–12 months as per regulatory standards
Decontamination: Before filter replacement, relocation, or servicing
General Cleaning: Daily/weekly, depending on lab protocols

A Biological Safety Cabinet (BSC) is a specialized containment unit that uses HEPA/ULPA filters and controlled airflow to protect laboratory staff, samples, and the environment from infectious aerosols. For buyers, it ensures regulatory compliance (NSF/EN standards), while for users, it provides a sterile, safe working environment essential in pharma QC, research, and diagnostics.

A biosafety cabinet (BSC) is engineered for biological protection (operator, environment, and product), whereas a fume hood is designed for chemical safety only. Many labs mistakenly interchange them, but procurement heads should note that installing the wrong system risks regulatory non-compliance, operator safety breaches, and costly retrofits.

• Class I BSC: Protects personnel & environment, but not the sample.
  
• Class II BSC: Protects personnel, product, and environment, the most widely used in pharma, biotech, and R&D.
• Class III BSC: Gas-tight, glove-box type for high-risk pathogens.

For decision-makers: Class II BSCs account for 70–80% of installations in Indian pharma & life sciences labs due to versatility.

A BSL-2 lab handles agents with moderate health risks (e.g., HIV, influenza, hepatitis). The Class II BSC is the industry standard here. Buyers should ensure suppliers provide certified airflow tests and HEPA leak testing, as regulatory audits often demand documented proof of compliance.

A Class II biosafety cabinet offers three-way protection: operator, environment, and product. These are critical in tissue culture labs, QC labs, vaccine production, molecular biology, and diagnostics. From a buyer’s perspective, ensure you choose between Type A2 (70% recirculation, energy efficient) and Type B2 (100% exhaust, suitable for volatile compounds) depending on application.

• Class I: Basic protection, often for low-level teaching labs.
  
• Class II: Balanced protection, ideal for most industrial and research labs.
• Class III: Maximum containment for BSL-3/BSL-4 pathogens.

Buyers should match cabinet type to lab biosafety level and not rely on cost alone, as wrong classification can lead to audit failures.

• A Class II Type A2 cabinet recirculates ~70% of filtered air and exhausts ~30%. It’s the default choice for most pharma, microbiology, and biotech applications. Procurement heads should confirm that vendors supply NSF49/EN12469-compliant A2 cabinets and provide commissioning certificates.

The Class II Type B2 cabinet exhausts 100% of air through HEPA filtration, making it suitable when biological hazards are handled alongside chemicals or radionuclides. This is costlier and requires dedicated ducting/ventilation,  so buyers must assess facility readiness and AMC costs before procurement.

A Class III BSC is a completely sealed, gas-tight unit operated through glove ports, designed for BSL-3 and BSL-4 labs handling pathogens such as SARS-CoV or Ebola. For buyers, these cabinets represent long lead times, custom builds, and stringent compliance,  ensure supplier has proven track record before placing orders.

Typical biosafety cabinet price range:

• Class I: ₹1.5 – 3 lakhs
  
  
• Class II A2: ₹3 – 6 lakhs
  
  
• Class II B2: ₹5 – 9 lakhs
• Class III: ₹15 lakhs+

Buyers must factor installation, calibration, and AMC into lifecycle cost. Lowest upfront price is not always lowest TCO (total cost of ownership).

Local manufacturers like Envigaurd ensure:

• Shorter lead times (4–6 weeks vs. 12–16 weeks for imports)
  
  
• On-site AMC, calibration, and filter replacement
  
  
• Compliance with Indian pharma audits & NABL standards
  
  

Customization for room size, ducting, and utility integration
For buyers, local sourcing significantly reduces downtime, maintenance costs, and compliance risks.

Class II A2 models require a stable electrical supply and proper clearance (typically 12–18 inches above the cabinet for exhaust airflow). Class II B2 models require ducting to the external exhaust system with continuous airflow monitoring. During installation, we ensure correct leveling, airflow calibration, and room pressurization checks. Final step includes site validation and operator training for safe use.

OPEX includes HEPA/ULPA filter replacement every 3–5 years, annual certification, AMC charges, and power consumption. Type B2 models have higher running costs due to 100% exhaust requirements. As manufacturers, we advise factoring in filter life, energy efficiency ratings, and service accessibility when evaluating lifecycle costs.

Yes. Our cabinets are designed and validated as per NSF 49 / EN 12469 standards, and we provide complete DQ/IQ/OQ/PQ documentation required for pharma GMP audits. During commissioning, we conduct HEPA integrity tests, airflow velocity measurement, and KI Discus tests to ensure compliance.

Reputed manufacturers (including us) provide comprehensive AMC packages covering preventive maintenance, calibration, and certification. We maintain in-stock spare parts and filters to reduce downtime. Our teams also offer emergency breakdown service and annual re-validation to keep labs compliant.

– Pharma & vaccine labs: Class II A2 or B2 (B2 preferred when working with volatile chemicals or toxic agents).
–Hospitals/diagnostics: Class II A2 (best balance of safety and efficiency).
– Teaching labs/academia: Class I (cost-effective, basic operator/environment protection).
Selection is finalized after a site survey and risk assessment by our engineering team.

Certified biosafety cabinets are delivered within 4–6 weeks. Installation, testing, and commissioning are completed in 2–3 days, including airflow calibration, filter integrity checks, and operator training.